Mariana Braga de Oliveira

Assistant Researcher

Ongoing Supervisions

Projects

Exploring devitalized MSCs fibres as immunomodulatory devices for wound regeneration through (i) direct promotion of healing or (ii) enabling of allograft transplantation free of systemic immunosuppression (LAZARUS)

CoordinatorOther International
The project aims at exploring MSCs as constituents of off-the-shelf easy-to-handle immunomodulatory biomaterials. The project focuses on using these materials to treat difficult-to-heal wounds, which may be chronic, or have proneness to become chronic if not properly treated.Two treatment approaches will be explored using devitalized MSC aggrega...

Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)

PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...

Innovative tools to treat and model complex cancer environments (TheraTools)

PartnerEuropean Comission
Funded by the Marie Skłodowska-Curie Actions programme, the TheraTools project will create a multidisciplinary research and training network to focus on the technological development of scientific tools to study malignant tumours localised beyond a biological barrier, as in the case of brain tumours. The TheraTools consortium will provi...

Merging Sustainable and Digital Chemical Technologies for The Development of Greener-Bydesign Pharmaceuticals (SusPharma)

PartnerEuropean Comission
Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern ...

Metabolite-activated 3D stem cell differentiation into bone (BetterBone)

PartnerFundação para a Ciência e a Tecnologia
Strategies involving mesenchymal stem cell (MSC) osteogenic differentiation have emerged as promising tools in regenerative medicine. These work by either promoting in situ regeneration, or through newly-fabricated tissue grafts, potentially overcoming clinical complications related to more conventional therapies. However, bioengineered ...

Publications

An Intracellular Metabolic Signature as a Potential Donor-Independent Marker of the Osteogenic Differentiation of Adipose Tissue Mesenchymal Stem Cells

Bispo, DSC; Jesus, CSH; Romek, K; Marques, IMC; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 23.

Cell Response in Free-Packed Granular Systems

Cunha, AF; Matias, AFV; Dias, CS; Oliveira, MB; Araujo, NAM; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 36, 40469-40480.

Cell Response in Free-Packed Granular Systems

Ana F. Cunha, André F. V. Matias, Cristóvão S. Dias, Mariana B. Oliveira*, Nuno A. M. Araújo*, João F. Mano*
2022, ACS Applied Materials & Interfaces, 14, 36, S417-S418.

Endo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation

Bispo, DSC; Michalkova, L; Correia, M; Jesus, CSH; Duarte, IF; Goodfellow, BJ; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 8.

NMR Metabolomics Assessment of Osteogenic Differentiation of Adipose-Tissue-Derived Mesenchymal Stem Cells

Bispo, DSC; Jesus, CSH; Correia, M; Ferreira, F; Bonifazio, G; Goodfellow, BJ; Oliveira, MB; Mano, JF; Gil, AM
2022, JOURNAL OF PROTEOME RESEARCH, 21, 3, 654-670.

ONE-STEP ASSEMBLY OF ROBUST ALL-CELLULAR FIBERS

Oliveira, MB; Salvador, T; Sousa, AR; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S398-S398.

Tricalcium phosphate doped with Mg2+ and combinations of Mn2+, Zn2+ and Fe3+: A DoE study on sintering, mechanical, microstructural and biological properties

Macedo, DF; Cunha, AF; Mano, JF; Oliveira, MB; Silva, AP
2022, CERAMICS INTERNATIONAL, 48, 14, 20467-20477.

Recent advances in the design of implantable insulin secreting heterocellular islet organoids

Akolpoglu, MB; Inceoglu, Y; Bozuyuk, U; Sousa, AR; Oliveira, MB; Mano, JF; Kizilel, S
2021, BIOMATERIALS, 269.
ISBN: 1878-5905

Engineering Strategies for Allogeneic Solid Tissue Acceptance

Sousa, AR; Mano, JF; Oliveira, MB
2021, TRENDS IN MOLECULAR MEDICINE, 27, 6, 572-587.
ISBN: 1471-499X

Strategies for re-vascularization and promotion of angiogenesis in trauma and disease

Goncalves, RC; Banfi, A; Oliveira, MB; Mano, JF
2021, BIOMATERIALS, 269.
ISBN: 1878-5905

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".