Ana Maria Ferreira Takahashi

Junior Researcher

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Department

  • Chemistry
  • 29.1.37

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Research

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short cv

I obtained my MSc degree in Chemical Engineering from the University of Aveiro in 2013. In July of 2018, I completed my PhD in Chemical Engineering at the University of Aveiro, funded by Fundação para a Ciência e Tecnologia (FCT) through a PhD scholarship. During the PhD I had the opportunity to broaden my scientific skills abroad, through trainees at Universidade Estadual Paulista, Brazil, and Tokyo University of Agriculture, Japan. After finishing my PhD, I moved to the Technical University of Munich (TUM, one of the world's top universities), Germany, as a postdoctoral researcher, to work on the purification of compounds from microalgae in collaboration with the company Oceanbasis, with a TUM University Foundation Fellowship. This fellowship is awarded once a year by TUM, where ca. 10 young scientists are selected from all over the world. Currently, I am a researcher at UA working in the chiral resolution of drugs by enantioselective aqueous biphasic systems, being the importance of this work recognized in the international conference Biopartitioning & Purification 2019 (BR) with the award for best presentation poster sponsored by Elsevier. Up to the data, I am in 2 funded R&D projects. I am PI of 1 funded project (POCI-01-0145-FEDER-030750, 239893 EUR), and team member in another funded project (POCI-01-0247-FEDER-045304, 297976 EUR) in collaboration with the company Mistolin. Overall, in these last years, I gathered a vast knowledge on the development of sustainable extraction/purification platforms (using both solid- and liquid-liquid extraction) of compounds from different matrices, showing my commitment to science in the benefit of the environment and society.

Since the beginning of my research activities, I filled 1 national patent, published 2 book chapters, 18 SCI papers and 1 journal cover, with 600+ citations and an h-index of 13. I have published in various high IF journals, namely Green Chem (IF 9.48, 8/18 SCI), ACS Sustain Chem Eng (IF 7.63), Chem Commun (IF 5.99), Sep Purif Technol (IF 5.77) and others. I am the first author in 9/18 SCI papers and worked with 43 co-authors. Moreover, I contributed with 90+ communications.

background

2014-2018: PhD in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

2008-2013: MSc in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

reserch group

Path 

Development of sustainable products and processes using alternative solvents 

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http://path.web.ua.pt

https://www.facebook.com/PATh.group

 

research area

Chemical Engineering

Development of innovative, integrated and sustainable processes for the extraction and separation of value-added compounds (alkaloids, amino acids, phenolic acids and others natural compounds) with therapeutic features from biomass, as well as wastes, using aqueous solutions of ionic liquids and surfactants, within a biorefinery perspective (circular economy).

 

Biotechnology

Development of cost-effective purification and recovery processes for several value‐added biopharmaceuticals, namely proteins, enzymes, antibodies, and nucleic‐acids‐based products.

 

Chemistry/Physical Chemistry

Understand the molecular‐level mechanisms which rule the liquid-liquid equilibria and the extraction performance of separation processes, by the determination of thermodynamic properties of solution, solvation and transfer.

selected publications

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supervision of students

MSc students

Isa R. M. Sucena, Valorizção de residuos plásticos: extração de corantes utilizando solventes alternativos, MSc Thesis in Chemical Engineering,  Supervisors: Dr. Ana M. Ferreira and Prof. Dr. João A.P. Coutinho, University of Aveiro, 2020/2021 (in progress).

Sandra Silva, De resíduos alimentares a compostos de valor acrescentado utilizando soluções aquosas de solventes alternativos, MSc Thesis in Biochemistry,  Supervisors: Dr. Ana M. Ferreira and Dr. Helena Passos, 2020/2021 (in progress).

Brayan Cruz, O efeito hidrotrópico de compostos zwiteriónicos no desenvolvimento de novas formulações farmacêuticas, MSc Thesis in Biochemistry, Supervisors: Dr. Helena Passos and Dr. Ana M. Ferreira, 2020/2021 (in progress).

Guilherme A. S. V. B. Barros, Extração de dopamina de fontes naturais com benefícios para a saúde, MSc Thesis in Chemical Engineering,  Supervisors: Dr. Ana M. Ferreira and Prof. Dr. João A.P. Coutinho, University of Aveiro, 2019/2020.

 

BSc students 

Ana S. F. Pinto, Avaliação do efeito hidrotrópico de compostos zwiteriónicos de baixa toxicidade para aplicação na indústria farmacêutica, Graduation in biochemistry, Supervisors: Dr. Helena Passos and Dr. Ana M. Ferreira, University of Aveiro, 2019/2020.

Tatiana D. Ferreira, Avaliação do efeito hidrotrópico de compostos zwiteriónicos de baixa toxicidade para aplicação na indústria farmacêutica, Graduation in biotechnology, Supervisors: Dr. Helena Passos and Dr. Ana M. Ferreira, University of Aveiro, 2019/2020.

journal covers

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Ongoing Supervisions

Ana Sofia Ferreira Pinto

MSc Student

Mahtab Moradi

PhD Student

Marina Setubal Justi

MSc Student

Projects

Publications

Efficient Extraction of the RuBisCO Enzyme from Spinach Leaves Using Aqueous Solutions of Biocompatible Ionic Liquids

Ana I. Valente, Ana M. Ferreira, Mafalda R. Almeida, Aminou Mohamadou, Mara G. Freire and Ana P. M. Tavares
2022, Sustainable Chemistry, 3, 1-18.

First Stage of the Development of an Eco-Friendly Detergent Formulation for Efficient Removal of Carbonized Soil

Fernandes, APM; Ferreira, AM; Sebastiao, M; Santos, R; Neves, CMSS; Coutinho, JAP
2022, MOLECULES, 27, 21.

Pretreatment of Plastic Waste: Removal of Colorants from HDPE Using Biosolvents

Ferreira, AM; Sucena, I; Otero, V; Angelin, EM; Melo, MJ; Coutinho, JAP
2022, MOLECULES, 27, 1.

The impact of size and shape in the performance of hydrotropes: a case-study of alkanediols

Abranches, DO; Soares, BP; Ferreira, AM; Shimizu, S; Pinho, SP; Coutinho, JAP
2022, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 24, 13, 7624-7634.

The impact of the counterion in the performance of ionic hydrotropes

Dinis O. Abranches, Jordana Benfica, Bruna P. Soares, Ana M. Ferreira, Tânia E. Sintra, Seishi Shimizu, João A. P. Coutinho
2021, Chemical Communications, 57, 2951-2954 .

Propranolol resolution using enantioselective biphasic systems

Carreira, ARF; Ferreira, AM; Almeida, MR; Coutinho, JAP; Sintra, TE
2021, SEPARATION AND PURIFICATION TECHNOLOGY, 254.
ISBN: 1873-3794

Zwitterionic compounds are less ecotoxic than their analogous ionic liquids

Jesus, F; Passos, H; Ferreira, AM; Kuroda, K; Pereira, JL; Goncalves, FJM; Coutinho, JAP; Ventura, SPM
2021, GREEN CHEMISTRY, 23, 10, 3683-3692.
ISBN: 1463-9270

Sustainable liquid supports for laccase immobilization and reuse: Degradation of dyes in aqueous biphasic systems

Ferreira, AM; Valente, AI; Castro, LS; Coutinho, JAP; Freire, MG; Tavares, APM
2021, BIOTECHNOLOGY AND BIOENGINEERING, 118, 7, 2514-2523.
ISBN: 1097-0290

Using COSMO-RS to Predict Solvatochromic Parameters for Deep Eutectic Solvents

Wojeicchowski, JP; Abranches, DO; Ferreira, AM; Mafra, MR; Coutinho, JAP
2021, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 9, 30, 10240-10249.

Integrated Biocatalytic Platform Based on Aqueous Biphasic Systems for the Sustainable Oligomerization of Rutin

Muniz-Mouro, A; Ferreira, AM; Coutinho, JAP; Freire, MG; Tavares, APM; Gullon, P; Gonzalez-Garcia, S; Eibes, G
2021, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 9, 29, 9941-9950.

Anti-Cancer Biosurfactants

In Springer (Eds.), Microbial Biosurfactants
Flávia F. Magalhães, João C. F. Nunes, Marília T. Araújo, Ana M. Ferreira, Mafalda R. Almeida, Mara G. Freire, Ana P. M. Tavares
2021, 159-196.
ISBN: 10.1007/978-981-15-6607-3_8

Purification, characterization and clinical applications of therapeutic fungal enzymes

In Pankaj Kumar Chaurasia and Shashi Lata Bharati (Eds.), Research Advances in the Fungal World: Culture, Isolation, Identification, Classification, Characterization, Properties and Kinetics
Mafalda R. Almeida, Ana M. Ferreira, João C. F. Nunes and Ana P. M. Tavares
2020, 273-320, Nova Science Publishers.
ISBN: 978-1-53617-197-6

Ionic Liquids Aqueous Solutions as Sustainable Solvents in Separation Processes

Ana Maria da Conceição Ferreira
2018, supervised by Mara G. Freire and João A. P. Coutinho.

Separation of dyes with reversible aqueous biphasic systems

Ana Maria da Conceição Ferreira
2013, supervised by Ana M. Fernandes and Mara G. Freire.

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