Ana Maria Ferreira Takahashi

Junior Researcher

short cv

I obtained my MSc degree in Chemical Engineering from the University of Aveiro in 2013. In July of 2018, I completed my PhD in Chemical Engineering at the University of Aveiro, funded by Fundação para a Ciência e Tecnologia (FCT) through a PhD scholarship. During the PhD I had the opportunity to broaden my scientific skills abroad, through trainees at Universidade Estadual Paulista, Brazil, and Tokyo University of Agriculture, Japan. After finishing my PhD, I moved to the Technical University of Munich (TUM, one of the world's top universities), Germany, as a postdoctoral researcher, to work on the purification of compounds from microalgae in collaboration with the company Oceanbasis, with a TUM University Foundation Fellowship. This fellowship is awarded once a year by TUM, where ca. 10 young scientists are selected from all over the world. Currently, I am a researcher at UA working in the chiral resolution of drugs by enantioselective aqueous biphasic systems, being the importance of this work recognized in the international conference Biopartitioning & Purification 2019 (BR) with the award for best presentation poster sponsored by Elsevier. Up to the data, I am in 2 funded R&D projects. I am PI of 1 funded project (POCI-01-0145-FEDER-030750, 239893 EUR), and team member in another funded project (POCI-01-0247-FEDER-045304, 297976 EUR) in collaboration with the company Mistolin. Overall, in these last years, I gathered a vast knowledge on the development of sustainable extraction/purification platforms (using both solid- and liquid-liquid extraction) of compounds from different matrices, showing my commitment to science in the benefit of the environment and society.

Since the beginning of my research activities, I filled 1 national patent, published 2 book chapters, 18 SCI papers and 1 journal cover, with 600+ citations and an h-index of 13. I have published in various high IF journals, namely Green Chem (IF 9.48, 8/18 SCI), ACS Sustain Chem Eng (IF 7.63), Chem Commun (IF 5.99), Sep Purif Technol (IF 5.77) and others. I am the first author in 9/18 SCI papers and worked with 43 co-authors. Moreover, I contributed with 90+ communications.


2014-2018: PhD in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

2008-2013: MSc in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

research area

Chemical Engineering

Development of innovative, integrated and sustainable processes for the extraction and separation of value-added compounds (alkaloids, amino acids, phenolic acids and others natural compounds) with therapeutic features from biomass, as well as wastes, using aqueous solutions of ionic liquids and surfactants, within a biorefinery perspective (circular economy).



Development of cost-effective purification and recovery processes for several value‐added biopharmaceuticals, namely proteins, enzymes, antibodies, and nucleic‐acids‐based products.


Chemistry/Physical Chemistry

Understand the molecular‐level mechanisms which rule the liquid-liquid equilibria and the extraction performance of separation processes, by the determination of thermodynamic properties of solution, solvation and transfer.

Ongoing Supervisions



Efficient Extraction of the RuBisCO Enzyme from Spinach Leaves Using Aqueous Solutions of Biocompatible Ionic Liquids

Ana I. Valente, Ana M. Ferreira, Mafalda R. Almeida, Aminou Mohamadou, Mara G. Freire and Ana P. M. Tavares
2022, Sustainable Chemistry, 3, 1-18.

First Stage of the Development of an Eco-Friendly Detergent Formulation for Efficient Removal of Carbonized Soil

Fernandes, APM; Ferreira, AM; Sebastiao, M; Santos, R; Neves, CMSS; Coutinho, JAP
2022, MOLECULES, 27, 21.

Pretreatment of Plastic Waste: Removal of Colorants from HDPE Using Biosolvents

Ferreira, AM; Sucena, I; Otero, V; Angelin, EM; Melo, MJ; Coutinho, JAP
2022, MOLECULES, 27, 1.

The impact of size and shape in the performance of hydrotropes: a case-study of alkanediols

Abranches, DO; Soares, BP; Ferreira, AM; Shimizu, S; Pinho, SP; Coutinho, JAP

The impact of the counterion in the performance of ionic hydrotropes

Dinis O. Abranches, Jordana Benfica, Bruna P. Soares, Ana M. Ferreira, Tânia E. Sintra, Seishi Shimizu, João A. P. Coutinho
2021, Chemical Communications, 57, 2951-2954 .

Propranolol resolution using enantioselective biphasic systems

Carreira, ARF; Ferreira, AM; Almeida, MR; Coutinho, JAP; Sintra, TE
ISBN: 1873-3794

Zwitterionic compounds are less ecotoxic than their analogous ionic liquids

Jesus, F; Passos, H; Ferreira, AM; Kuroda, K; Pereira, JL; Goncalves, FJM; Coutinho, JAP; Ventura, SPM
2021, GREEN CHEMISTRY, 23, 10, 3683-3692.
ISBN: 1463-9270

Sustainable liquid supports for laccase immobilization and reuse: Degradation of dyes in aqueous biphasic systems

Ferreira, AM; Valente, AI; Castro, LS; Coutinho, JAP; Freire, MG; Tavares, APM
ISBN: 1097-0290

Using COSMO-RS to Predict Solvatochromic Parameters for Deep Eutectic Solvents

Wojeicchowski, JP; Abranches, DO; Ferreira, AM; Mafra, MR; Coutinho, JAP

Integrated Biocatalytic Platform Based on Aqueous Biphasic Systems for the Sustainable Oligomerization of Rutin

Muniz-Mouro, A; Ferreira, AM; Coutinho, JAP; Freire, MG; Tavares, APM; Gullon, P; Gonzalez-Garcia, S; Eibes, G

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