Desenvolvimento de vectores magnéticos nanopartículas-virus para geneterapia do cérebro senil (EULANEST European-Latin American Network for Science and Technology)
tipo de financiamento European Comission
programa FP6/ERANET/EULANEST Network
referência alternative ERA-Eula/0003/2009
grupo(s) de investigação 1 - nanomateriais inorgânicos funcionais e híbridos orgânico-inorgânico;
departamento Chemistry (DQ)
período de execução 2010-06-25 - 2012-12-31 ( 30 Meses )
data de extensão projeto 2013-06-30 ( 6 Meses extra )
Creating an European - Latin American network to develop a new gene therapy strategy for the treatment of neurodegenerative diseases
A number of age-related neurological pathologies are of significant medical and economic impact for both Latin American and European regions due to the increase of the elderly population in urban areas. Therefore, the development of novel therapies for neurodegenerative diseases constitutes an issue of growing importance.
Neuronano is a multidisciplinary project aimed to develop new gene therapy-related therapeutic strategies for the treatment of neurodegenerative diseases. Using tools from nanotechnology, nanomagnetism and gene therapy we propose to construct novel, high performance magnetic adenoviral vectors for magnetotransduction, to enhance the levels of neurotrophic factors that prevent the degeneration and enhance recovery of remaining neuron neuroprotective molecules. Starting by animal models of senile neurodegeneration, this therapy could be ultimately used in Alzheimer and Parkinsonian patients.
Among the key outcomes of the project will be the establishment of a collaborative network involving scientific partners from Europe and Latin America, to provide a suitable framework for dissemination activities and training of young researches with multidisciplinary profile.
/ip local
Tito Trindade
ciceco status Parceiro
instituíção proponente University of Zaragoza (Spain)
instituições participante(s) Technical University of Munich (Germany); University of Aveiro (Portugal); National University of La Plata (Argentina)
participação industrial Não
parceiro(s) internacional Sim
orçamento total 1.934.998€
orçamento ciceco 39.900€
centro de custos 3.89.154