authors |
Ventura, SPM; Silva, FAE; Quental, MV; Mondal, D; Freire, MG; Coutinho, JAP |
nationality |
International |
journal |
CHEMICAL REVIEWS |
keywords |
AQUEOUS 2-PHASE SYSTEMS; ULTRASONIC-ASSISTED EXTRACTION; SOLID-PHASE EXTRACTION; BOVINE SERUM-ALBUMIN; ACID METHYL-ESTERS; CITRUS ESSENTIAL OIL; 3-PHASE PARTITIONING ILTPP; SALVIA-MILTIORRHIZA-BUNGE; FLAVUM CR. PAPAVERACEAE; COUNTER-CURRENT CHROMATOGRAPHY |
abstract |
Ionic liquids (ILs) have been proposed as promising media for the extraction and separation of bioactive compounds from the most diverse,origins. This critical review offers a compilation on the main results achieved by the use of ionic liquid-based processes in the extraction and separation/purification of a large range of bioactive compounds (including small organic extractable compounds from biomass, lipids, and other hydrophobic compounds, proteins, amino acids, nucleic acids, and pharmaceuticals). ILs have been studied as solvents, cosolvents, cosurfactants, electrolytes, and adjuvants, as well as used in the creation of IL-supported materials for separation purposes. The IL-based processes hitherto reported, such as IL-based solid liquid extractions, IL-based liquid-liquid extractions, IL-modified materials, and IL-based crystallization approaches, are here reviewed and compared in terms of extraction and separation performance. The key accomplishments and future challenges to the field are discussed, with particular emphasis on the major lacunas found within the IL community dedicated to Separation processes and by suggesting some steps to overcome the current limitations. |
publisher |
AMER CHEMICAL SOC |
issn |
Sep-65 |
isbn |
1520-6890 |
year published |
2017 |
volume |
117 |
issue |
10 |
beginning page |
6984 |
ending page |
7052 |
digital object identifier (doi) |
10.1021/acs.chemrev.6b00550 |
web of science category |
Chemistry, Multidisciplinary |
subject category |
Chemistry |
unique article identifier |
WOS:000402498700008
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ciceco authors
impact metrics
journal analysis (jcr 2019):
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journal impact factor |
52.758 |
5 year journal impact factor |
60.399 |
category normalized journal impact factor percentile |
99.718 |
dimensions (citation analysis):
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altmetrics (social interaction):
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