Ongoing Supervisions
João António Abreu Pereira
PhD Student
Patrícia Coelho Vigário
Research Fellowship
Rita Moreira
PhD StudentProjects
A bioprinting platform for the rapid, reliable, controlled and quantifiable patterning of cellular aggregatesand microtissues into macroscale regenerative grafts with programmable architectures (m2M)
PartnerEuropean Comission
A fundamental limitation with current approaches aiming to bioprint tissues and organs is an inability to generate constructs with truly biomimetic composition and structure, resulting in the development of engineered tissues that cannot execute their specific function in vivo. This is perhaps unsurprising, as many tissues and organs co...Development of a multifunctional biomaterial patch for buccal delivery of peptide-analogue treatments (BUCCAL-PEP)
PartnerEuropean Comission
Oral delivery of peptide macromolecules represents significant challenges for pharmaceutical research, including low bioavailability, dosage control and undesirable food interactions. The intention of the EU-funded BUCCAL-PEP project is to develop a technological platform for oromucosal delivery suitable for a broad range of peptide-ana...Full human-based multi-scale constructs with jammed regenerative pockets for bone engineering (REBORN)
PartnerEuropean Comission
Engineered bone tissue has many advantages over natural bone grafts, including safety and limitless supply. However, current engineering methods cannot generate large vascularised grafts capable of in vivo integration and remodelling. To address this problem, the EU-funded REBORN project proposes to combine biomaterials based on protein...Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)
PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
magnetic; 3D cell colonization; hydrogelBioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)
PartnerFundação para a Ciência e a Tecnologia
The driving force behind TETRISSUE is inspired in the fundamentals of the native bone regenerative process and supported by a strong technological character to produce highly vascularized ultrastructured bone replacements. Its innovative character is mainly related with the integration of key elements working in tandem: (1) bioinstructi...Publications
Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies
Elisa A.G. Martins, Inês A. Deus, Maria C. Gomes, Ana S. Silva, João F. Mano, and Catarina A. Custódio
2024, Advanced Healthcare Materials, 2401510.
Biomimetic Adhesive Micropatterned Hydrogel Patches for Drug Release
Amaral, KR; Silva, AS; Santos, LF; Castanheira, EJ; Mendes, MC; Costa, DCS; Rodrigues, JMM; Marto, J; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 28.
Magnetic-Based Strategies for Regenerative Medicine and Tissue Engineering
Santos, LF; Silva, AS; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 25.
BIOACTIVE MEMBRANES FOR THE FUTURE TREATMENT OF OSTEOPOROTIC FRACTURES.
Silva, AS; Santos, LF; Cunha, AL; Nadine, S; Correia, CR; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S279-S279.
Bioengineered Hierarchical Bonelike Compartmentalized Microconstructs Using Nanogrooved Microdiscs
Bjorge, IM; de Sousa, BM; Patricio, SG; Silva, AS; Nogueira, LP; Santos, LF; Vieira, SI; Haugen, HJ; Correia, CR; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 17, 19116-19128.
Freestanding Magnetic Microtissues for Tissue Engineering Applications
Santos, LF; Patricio, SG; Silva, AS; Mano, JF
2022, ADVANCED HEALTHCARE MATERIALS, 11, 8.
Self-glucose feeding hydrogels by enzyme empowered degradation for 3D cell culture
Zargarzadeh, M; Silva, AS; Nunes, C; Coimbra, MA; Custodio, CA; Mano, JF
2022, MATERIALS HORIZONS, 9, 2, 694-707.
Inhalable hydrophilic molecule-loaded liposomal dry powder formulations using supercritical CO2 – assisted spray-drying
Clarinda Costa, Beatriz Nobre, Ana Sofia Matos, Ana SofiaSilva, TeresaCasimiro, Maria Luísa Corvo Ana Aguiar-Ricardo
2021, Journal of CO2 Utilization.
Inhalable hydrophilic molecule-loaded liposomal dry powder formulations using supercritical CO2-assisted spray-drying
Costa, C; Nobre, B; Matos, AS; Silva, AS; Casimiro, T; Corvo, ML; Aguiar-Ricardo, A
2021, JOURNAL OF CO2 UTILIZATION, 53.
ISBN:
2212-9839
Multi-layer pre-vascularized magnetic cell sheets for bone regeneration
Silva, AS; Santos, LF; Mendes, MC; Mano, JF
2020, BIOMATERIALS, 231.
ISBN:
1878-5905
