Ana Sofia Matias da Silva

Assistant Researcher

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Department

  • Chemistry
  • 29.3.38

Research

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Latest News

Ongoing Supervisions

João António Abreu Pereira

PhD Student

Projects

Development of a multifunctional biomaterial patch for buccal delivery of peptide-analogue treatments (BUCCAL-PEP)

PartnerEuropean Comission
Oral delivery of peptide macromolecules represents significant challenges for pharmaceutical research, including low bioavailability, dosage control and undesirable food interactions. The intention of the EU-funded BUCCAL-PEP project is to develop a technological platform for oromucosal delivery suitable for a broad range of peptide-ana...

Full human-based multi-scale constructs with jammed regenerative pockets for bone engineering (REBORN)

PartnerEuropean Comission
Engineered bone tissue has many advantages over natural bone grafts, including safety and limitless supply. However, current engineering methods cannot generate large vascularised grafts capable of in vivo integration and remodelling. To address this problem, the EU-funded REBORN project proposes to combine biomaterials based on proteins obtaine...

Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)

PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...

3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)

PartnerFundação para a Ciência e a Tecnologia
Maritime Domain Awareness is the combination of activities, events and threats in the maritime environment that could have impact on marine activities and EU territory. During the past decades, advances in Information and Communication Technologies have provided better means to monitor and analyse vessel activity. Today private and public source...

Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)

PartnerFundação para a Ciência e a Tecnologia
The driving force behind TETRISSUE is inspired in the fundamentals of the native bone regenerative process and supported by a strong technological character to produce highly vascularized ultrastructured bone replacements. Its innovative character is mainly related with the integration of key elements working in tandem: (1) bioinstructive microp...

Publications

Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies

Martins, EAG; Deus, IA; Gomes, MC; Silva, AS; Mano, JF; Custódio, CA
2025, ADVANCED HEALTHCARE MATERIALS, 14, 1.
ISBN: 2192-2659

Magneto-Enzymatic Microgels for Precise Hydrogel Sculpturing

Mendes, MC; Pereira, JA; Silva, AS; Mano, JF
2024, ADVANCED MATERIALS, 36, 41.
ISBN: 1521-4095

Biomimetic Adhesive Micropatterned Hydrogel Patches for Drug Release

Amaral, KR; Silva, AS; Santos, LF; Castanheira, EJ; Mendes, MC; Costa, DCS; Rodrigues, JMM; Marto, J; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 28.

Magnetic-Based Strategies for Regenerative Medicine and Tissue Engineering

Santos, LF; Silva, AS; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 25.

BIOACTIVE MEMBRANES FOR THE FUTURE TREATMENT OF OSTEOPOROTIC FRACTURES.

Silva, AS; Santos, LF; Cunha, AL; Nadine, S; Correia, CR; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S279-S279.

Bioengineered Hierarchical Bonelike Compartmentalized Microconstructs Using Nanogrooved Microdiscs

Bjorge, IM; de Sousa, BM; Patricio, SG; Silva, AS; Nogueira, LP; Santos, LF; Vieira, SI; Haugen, HJ; Correia, CR; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 17, 19116-19128.

Freestanding Magnetic Microtissues for Tissue Engineering Applications

Santos, LF; Patricio, SG; Silva, AS; Mano, JF
2022, ADVANCED HEALTHCARE MATERIALS, 11, 8.

Self-glucose feeding hydrogels by enzyme empowered degradation for 3D cell culture

Zargarzadeh, M; Silva, AS; Nunes, C; Coimbra, MA; Custodio, CA; Mano, JF
2022, MATERIALS HORIZONS, 9, 2, 694-707.

Inhalable hydrophilic molecule-loaded liposomal dry powder formulations using supercritical CO2 – assisted spray-drying

Clarinda Costa, Beatriz Nobre, Ana Sofia Matos, Ana SofiaSilva, TeresaCasimiro, Maria Luísa Corvo Ana Aguiar-Ricardo
2021, Journal of CO2 Utilization.

Inhalable hydrophilic molecule-loaded liposomal dry powder formulations using supercritical CO2-assisted spray-drying

Costa, C; Nobre, B; Matos, AS; Silva, AS; Casimiro, T; Corvo, ML; Aguiar-Ricardo, A
2021, JOURNAL OF CO2 UTILIZATION, 53.
ISBN: 2212-9839

Cell-based soft biomaterials

Soft Matter for Biomaterial Applications
A. Sofia Silva, Lúcia F. Santos, Mariana B. Oliveira and João F. Mano
2021.
ISBN: 978-1-78801-757-2

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