Ongoing Supervisions
Projects
Development of a multifunctional biomaterial patch for buccal delivery of peptide-analogue treatments (BUCCAL-PEP)
PartnerEuropean Comission
Oral delivery of peptide macromolecules represents significant challenges for pharmaceutical research, including low bioavailability, dosage control and undesirable food interactions. The intention of the EU-funded BUCCAL-PEP project is to develop a technological platform for oromucosal delivery suitable for a broad range of peptide-ana...Full human-based multi-scale constructs with jammed regenerative pockets for bone engineering (REBORN)
PartnerEuropean Comission
Engineered bone tissue has many advantages over natural bone grafts, including safety and limitless supply. However, current engineering methods cannot generate large vascularised grafts capable of in vivo integration and remodelling. To address this problem, the EU-funded REBORN project proposes to combine biomaterials based on proteins obtaine...Microdispositivos magneto-enzimáticos revolucionários: Avanços pioneiros em teragnóstica de tecidos profundos (WALKTHROUGH)
CoordinatorFundação para a Ciência e a Tecnologia
3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
Maritime Domain Awareness is the combination of activities, events and threats in the maritime environment that could have impact on marine activities and EU territory. During the past decades, advances in Information and Communication Technologies have provided better means to monitor and analyse vessel activity. Today private and public source...Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)
PartnerFundação para a Ciência e a Tecnologia
The driving force behind TETRISSUE is inspired in the fundamentals of the native bone regenerative process and supported by a strong technological character to produce highly vascularized ultrastructured bone replacements. Its innovative character is mainly related with the integration of key elements working in tandem: (1) bioinstructive microp...Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)
PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...Publications
Osteogenic Differentiation Triggered by Intracellular Magnetoelectric Stimulation of Core-Shell Nanotransducers under Remotely Applied Magnetic Fields
Mendes, MC; Martins, EAG; Chernozem, RV; Chernozem, PV; Custodio, CC; Surmenev, RA; Kholkin, AL; Silva, AS; Mano, JF
2025, ACS NANO, 19, 50, 42022-42045.
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Remote-Controlled Magnetic Stimulation of Cell-Based Bioengineered Tissues for In Situ Bone Regeneration
Santos, LF; Mendes, MC; Pereira, JA; Dias, IR; Viegas, CA; Amorim, CO; Amaral, JS; Nogueira, LP; Hauge, HJ; Silva, AS; Mano, JF
2025, ADVANCED MATERIALS, 37, 39.
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Advanced Injectable Human-Derived Microgels for Improved Cell Delivery and Tissue Regeneration
Mendes, MC; Santos, SC; Custódio, CA; Silva, AS; Mano, JF
2025, ADVANCED HEALTHCARE MATERIALS, 14, 25.
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Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies
Martins, EAG; Deus, IA; Gomes, MC; Silva, AS; Mano, JF; Custódio, CA
2025, ADVANCED HEALTHCARE MATERIALS, 14, 1.
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Magneto-Enzymatic Microgels for Precise Hydrogel Sculpturing
Mendes, MC; Pereira, JA; Silva, AS; Mano, JF
2024, ADVANCED MATERIALS, 36, 41.
ISBN:
1521-4095
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Biomimetic Adhesive Micropatterned Hydrogel Patches for Drug Release
Amaral, KR; Silva, AS; Santos, LF; Castanheira, EJ; Mendes, MC; Costa, DCS; Rodrigues, JMM; Marto, J; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 28.
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Magnetic-Based Strategies for Regenerative Medicine and Tissue Engineering
Santos, LF; Silva, AS; Mano, JF
2023, ADVANCED HEALTHCARE MATERIALS, 12, 25.
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BIOACTIVE MEMBRANES FOR THE FUTURE TREATMENT OF OSTEOPOROTIC FRACTURES.
Silva, AS; Santos, LF; Cunha, AL; Nadine, S; Correia, CR; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S279-S279.
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Bioengineered Hierarchical Bonelike Compartmentalized Microconstructs Using Nanogrooved Microdiscs
Bjorge, IM; de Sousa, BM; Patricio, SG; Silva, AS; Nogueira, LP; Santos, LF; Vieira, SI; Haugen, HJ; Correia, CR; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 17, 19116-19128.
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Freestanding Magnetic Microtissues for Tissue Engineering Applications
Santos, LF; Patricio, SG; Silva, AS; Mano, JF
2022, ADVANCED HEALTHCARE MATERIALS, 11, 8.
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