Ongoing Supervisions
Projects
Bioengenharia de materiais vivos compostos por células imunes para imunoterapia do cancro do pâncreas (ALIVE)
CoordinatorFundação para a Ciência e a Tecnologia
Bioengenharia de modelos ósseos biomiméticos para o desenvolvimento de terapias anti-tumorais e regenerativas (ÉLPIS)
PartnerOther National
Metastasis Exploration in the Bone Microenvironment - Breast Cancer Edition (METABONE)
PartnerFundação para a Ciência e a Tecnologia
METABONE is a collaborative research project that is all about creating a 3D model in a lab to explore how breast cancer spreads to the bones. To do this, we are using robots to automate tiny tasks and clever liquid capsules that act like mini-labs. The goal is to get an accurate picture of the complex bone environment. This platform is...Supramolecular design of multitactic 3D polymeric biomaterials for spinal cord repair (SUPRANEURO 2)
PartnerFundação para a Ciência e a Tecnologia
Spinal cord injury (SCI) represents one of the leading causes of disability worldwide , being characterized by a permanent loss of motor function and sensory perception owing to the complex pathophysiology and inability of the central nervous system (CNS) to self-regenerate. Currently, the most common therapeutic approaches involve the ...Sustainable 4D hydrogels functionalised with plant-based nanoparticles for bone regeneration in cancer patients (GreenNanoBone)
PartnerEuropean Comission
Biocompatible 4D materials for bone regeneration in MRONJ patients Medication-related osteonecrosis of the jaw (MRONJ) is a rare but severe side effect of bone-targeting agents (BTAs) such as bisphosphonates, prescribed to breast cancer survivors to lower the risk of secondary bone cancer. MRONJ can cause progressive jawbone destruction, leading...Unprecedented photolithographic structuring of novel light-sensitive poly(amino acid) materials- a paradigm shift in delivering biocompatible devices (POLINA)
Local CoordinatorEuropean Comission
Photolitography, which produces geometrical structures through light-induced polymerisation of monomers with high accuracy, precision and spatial resolution, was a key innovation enabler in the drive for high-performance miniature electronics, which had an unprecedented impact on every aspect of our modern life. Geometrically well-defined micros...3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
Maritime Domain Awareness is the combination of activities, events and threats in the maritime environment that could have impact on marine activities and EU territory. During the past decades, advances in Information and Communication Technologies have provided better means to monitor and analyse vessel activity. Today private and public source...Advancing the Regenerative and Translational Potential of Cellular Fibers (CellFi)
PartnerFundação para a Ciência e a Tecnologia
Mesenchymal Stem Cells Scaffold-free Cellular Fibers RegenerationDevelopment of 4D wireless thermometry to target tumor ablation (PTDC/NAN-MAT/3901/2020)
PartnerFundação para a Ciência e a Tecnologia
Thermography Magnetic Nanoparticles Induced Hyperthermia BioprintingDispositivos Supramoleculares Auto-Regulados baseados na Complementaridade dos Pares de Base do ADN: Uma Tecnologia Biomimética e com Reconheciemnto Molecular para Isolar Células Específicas para Aplicações Biomédicas (SUPRASORT)
PartnerFundação para a Ciência e a Tecnologia
Hydralazine: Testing an off-label effect in Castration-Resistant Prostate Cancer (HyTherCaP)
PartnerFundação para a Ciência e a Tecnologia
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related deaths among men. In Portugal, it is the most incident cancer and the 3rd cause of death (1, 2). Although most of PCa are clinically indolent, a variable proportion of patients develop castration-resistant PCa (CRPC), an aggre...Integrated photonic neuronal probes towards neuromorphic computing (PHEASANT)
PartnerFundação para a Ciência e a Tecnologia
Optical methods have been widely used for stimulation and functional imaging of neural circuits, namely, optogenetics which is a powerful tool for selective excitation or inhibition of specific cell types using light of different wavelengths desirable to stimulate or inhibit a subset of neurons that express the same light-sensitive proteins. The...Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Publications
Embedded Bioprinting of Tumor-Scale Pancreatic Cancer-Stroma 3D Models for Preclinical Drug Screening
Monteiro, MV; Rocha, M; Carvalho, MT; Freitas, I; Amaral, AJR; Sousa, FL; Gaspar, VM; Mano, JF
2024, ACS APPLIED MATERIALS & INTERFACES, 16, 42, 56718-56729.
ISBN:
1944-8252
>
Embedded 3D Bioprinting for Engineering Miniaturized In Vitro Tumor Models
Monteiro M.V.; Rocha M.; Gaspar V.M.; Mano J.F.
2024, Methods in molecular biology.
>
Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research
Ferreira, T; Gama, A; Seixas, F; Faustino-Rocha, AI; Lopes, C; Gaspar, VM; Mano, JF; Medeiros, R; Oliveira, PA
2023, VETERINARY SCIENCES, 10, 6.
>
Novel Insights on the Role of Epigenetics in Androgen Receptor's Expression in Prostate Cancer
Camilo, V; Pacheco, MB; Moreira-Silva, F; Outeiro-Pinho, G; Gaspar, VM; Mano, JF; Marques, CJ; Henrique, R; Jerónimo, C
2023, BIOMOLECULES, 13, 10.
>
Brewer's Spent Yeast Cell Wall Polysaccharides as Vegan and Clean Label Additives for Mayonnaise Formulation
Reis, SF; Fernandes, PAR; Martins, VJ; Gonçalves, S; Ferreira, LP; Gaspar, VM; Figueira, D; Castelo-Branco, D; Mano, JF; Coimbra, MA; Coelho, E
2023, MOLECULES, 28, 8.
>
Programmable Granular Hydrogel Inks for 3D Bioprinting Applications
Ribeiro, LS; Gaspar, VM; Sobreiro-Almeida, R; Camargo, ER; Mano, JF
2023, ADVANCED MATERIALS TECHNOLOGIES.
>
Development Control and Inactivation of Byssochlamys nivea Ascospores by Hyperbaric Storage at Room Temperature
Pinto, CA; Galante, D; Espinoza-Suarez, E; Gaspar, VM; Mano, JF; Barba, FJ; Saraiva, JA
2023, FOODS, 12, 5.
>
Double-Interlinked Colloidal Gels for Programable Fabrication of Supraparticle Architectures
Gonçalves, L; Lavrador, P; Amaral, AJR; Ferreira, LP; Gaspar, VM; Mano, JF
2023, ADVANCED FUNCTIONAL MATERIALS, 33, 45.
>
Cell Surface Engineering Tools for Programming Living Assemblies
Almeida-Pinto, J; Lagarto, MR; Lavrador, P; Mano, JF; Gaspar, VM
2023, ADVANCED SCIENCE, 10, 34.
>
3D-bioprinted cancer-on-a-chip: level-up organotypic in vitro models
Monteiro, MV; Zhang, YS; Gaspar, VM; Mano, JF
2022, TRENDS IN BIOTECHNOLOGY, 40, 4, 432-447.
>







