Silicon-phosphorus-calcium glass with high magnesium content for biomedical applications


The present invention relates to the process for obtaining a silicon-phosphorus-calcium glass with high magnesium content for biomedical applications, which is a two-phase glass with composition (wt%) 30,00% SiO2: 30,00% CaO: 22,75% P2O5: 17,25% MgO. This material has potential applications in dentistry and as a bone substitute for filling cavities. Its surface activity, responsible for the bioactivity, is controlled by a disproportionation mechanism of the silicon ion in the glass network.

Innovative aspects & main advantages

The glass of the present invention is a material with potential for biomedical applications, particularly in dentistry and bone reconstruction. The novelty lies in the fact that it has a much lower proportion of silica than the known bioactive glasses now clinically applied and a percentage of MgO much higher than the limit indicated in the literature as required to induce apatite precipitation in synthetic plasma. It is this MgO content that allows to control the degradability and the bioactivity of the glass in aqueous media.


Biomaterials; biomedical devices.


Fernandes, Maria; Correia, Rui; Oliveira, José

Our Inventors


Universidade de Aveiro
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