Ongoing Supervisions
Projects
Biomateriais Supramoleculares Quimicamente Programáveis e Dinâmicos para Regeneração Neuronal (SUPRANEURO)
CoordinatorFundação para a Ciência e a Tecnologia
Revolucionando Modelos de Doenças e Triagem de Medicamentos com um Sistema Microfisiológico Cardíaco Totalmente Humano Impresso em 3D. (CardioChip)
PartnerFundação para a Ciência e a Tecnologia
Supramolecular design of multitactic 3D polymeric biomaterials for spinal cord repair (SUPRANEURO 2)
CoordinatorFundação para a Ciência e a Tecnologia
Spinal cord injury (SCI) represents one of the leading causes of disability worldwide , being characterized by a permanent loss of motor function and sensory perception owing to the complex pathophysiology and inability of the central nervous system (CNS) to self-regenerate. Currently, the most common therapeutic approaches involve the ...3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
Maritime Domain Awareness is the combination of activities, events and threats in the maritime environment that could have impact on marine activities and EU territory. During the past decades, advances in Information and Communication Technologies have provided better means to monitor and analyse vessel activity. Today private and public source...Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)
PartnerFundação para a Ciência e a Tecnologia
The driving force behind TETRISSUE is inspired in the fundamentals of the native bone regenerative process and supported by a strong technological character to produce highly vascularized ultrastructured bone replacements. Its innovative character is mainly related with the integration of key elements working in tandem: (1) bioinstructive microp...CIRCUS - Directing Bone Dynamics Through The Synergistic Action Of Immune Cells With Bioengineered Cell Microfactories Containing Patterned Microplatforms (CIRCUS)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de uma membrana periodontal multicamada composta por blocos inovativos a base de polimeros de origem marinha e enzima para regeneracao guiada de osso que possui mineralizacao enzimatica controlada. (MIMETIc)
PartnerFundação para a Ciência e a Tecnologia
Dispositivos Supramoleculares Auto-Regulados baseados na Complementaridade dos Pares de Base do ADN: Uma Tecnologia Biomimética e com Reconheciemnto Molecular para Isolar Células Específicas para Aplicações Biomédicas (SUPRASORT)
CoordinatorFundação para a Ciência e a Tecnologia
Hidrogéis de Lisados de Plaquetas para Regeneração do Miocárdio (BEAT)
PartnerFundação para a Ciência e a Tecnologia
In the field of the Electronic Integrated circuit design, the analog-mixed-signal (AMS) physical design of all analog blocks and of whole integrated circuits (IC) based on the Analog-on-Top approach still uses a handmade flow. The Electronic Design Automation (EDA) industry has been working since several years in the application of techniques to...Marine Origin Biopolymers as Innovative Building Blocks from the Sea for the Development of Bioresorbable Multilayered Membranes for guided bone regeneration (BLUETEETH)
PartnerFundação para a Ciência e a Tecnologia
Natural origin polymers from algae and arthropods can be obtained in large scale, and a great effort has been paid to find applications for such high-added value materials. Periodontal disease is frequent in humans and constitutes, together with dental caries, the principal cause of tooth loss in adults. Currently, one of the available treatment...Metodologias eficientes para a conjugação de polissacarídeos naturais com péptidos para obtenção de membranas multifuncionais para regeneração periodontal. (COP2P)
PartnerFundação para a Ciência e a Tecnologia
Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Unlocking the scientific excellence and innovation capacity of the University of Aveiro in supramolecular multicomponent biomaterials for enabling advanced biomaterials for healthcare (SUPRALIFE)
CoordinatorEuropean Comission
The SUPRALIFE project is a Twinning project funded by the European Union’s Horizon Europe research and innovation programme which is coordinated by the COMPASS Research Group at CICECO, at the University of Aveiro (UAVR, Portugal). The consortium also brings together the Eindhoven University of Technology (TU/e, The Netherlands), the U...Publications
Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies
Vera Sousa, Rita Sobreiro-Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano
2026, Advanced Materials.
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Merging Natural Biopolymers with Supramolecular Chemistry: Emulating the Native Extracellular Matrix's Complexity
Sousa, V; Ladeira, B; Garanger, E; Lecommandoux, S; Meijer, EW; Dankers, PYW; Mano, JF; Borges, J
2025, ACS NANO, 19, 33, 29833-29859.
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Injectable and self-healable supramolecular hydrogels assembled by quaternised chitosan/alginate polyelectrolyte complexation for sustained drug delivery and cell encapsulation
Sousa, CFV; Borges, J; Mano, JF
2025, BIOMATERIALS SCIENCE, 13, 13, 3617-3632.
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Silk Sericin/Chitosan Supramolecular Multilayered Thin Films as Sustainable Cytocompatible Nanobiomaterials
Rosas, M; Sousa, CFV; Pereira, A; Amaral, AR; Pesqueira, T; Patrício, SG; Fateixa, S; Nogueira, HIS; Mano, JF; Oliveira, AL; Borges, J
2025, BIOMACROMOLECULES, 26, 1, 296-310.
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Marine-Origin Polysaccharides and Their Chemically Modified Derivatives as Sources of Advanced Biofunctional Materials for Biomedical Applications
Sousa, V; Monteiro, LPG; Rocha, DHA; Rodrigues, JMM; Borges, J; Mano, JF
2025, BIOMACROMOLECULES, 26, 8, 4735-4772.
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Natural Polymer-Polyphenol Bioadhesive Coacervate with Stable Wet Adhesion, Antibacterial Activity, and On-Demand Detachment
Sacramento, MMA; Oliveira, MB; Gomes, JRB; Borges, J; Freedman, BR; Mooney, DJ; Rodrigues, JMM; Mano, JF
2024, ADVANCED HEALTHCARE MATERIALS, 13, 13.
ISBN:
2192-2659
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Acidochromic Free-Standing Multilayered Chitosan-Pyranoflavylium/Alginate Membranes toward Food Smart Packaging Applications
Cunha, M; de Freitas, V; Borges, J; Mano, JF; Rodrigues, JMM; Cruz, L
2024, ACS APPLIED POLYMER MATERIALS, 6, 11, 6820-6830.
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Building the Young Program for IUPAC|CHAINS 2023
João Borges, Eva Meeus, Maximilian Menche, Fatima Mustafa, Koen Van den Helder
2024, ChemistryViews.
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Recent Developments in Layer-by-Layer Assembly for Drug Delivery and Tissue Engineering Applications
Borges, J; Zeng, JF; Liu, XQ; Chang, H; Monge, C; Garot, C; Ren, KF; Machillot, P; Vrana, NE; Lavalle, P; Akagi, T; Matsusaki, M; Ji, J; Akashi, M; Mano, JF; Gribova, V; Picart, C
2024, ADVANCED HEALTHCARE MATERIALS, 13, 8.
ISBN:
2192-2659
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Towards a Sustainable Future: Challenges and Opportunities for Early-Career Chemists
Dobbelaar, E; Goher, SS; Vidal, JL; Obhi, NK; Felisilda, BMB; Choo, YSL; Ismail, H; Lee, HL; Nascimento, V; Al Bakain, R; Ranasinghe, M; Davids, BL; Naim, A; Offiong, NA; Borges, J; John, T
2024, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 63, 35.
ISBN:
1521-3773
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Extending the Functionality of Marine-origin Polysaccharides Through Chemical Modification for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
João M. M. Rodrigues, Edgar J. Castanheira, Dora C. S. Costa, Djenisa H. A. Rocha, João Borges and João F. Mano
2021, 180-204, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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Shaping Soft Structures Using Bottom-up Layer-by-layer Assembly Technology for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
João Borges, Cristiana F. V. Sousa, Isabel M. Bjørge, Sara Nadine, Clara R. Correia, Sónia G. Patrício and João F. Mano
2021, 444-473, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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Stimuli-responsive Nanocomposite Hydrogels Incorporating Soft Nanoparticles for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
Pedro Lavrador, João Borges, Vítor M. Gaspar and João F. Mano
2021, 566-593, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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