Novel 3D platforms to engineer bone microtissues for in vitro disease models

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Project Details

Start date
2018-03-01
End date
2019-08-31
%
Acronym
Microbone
Reference
789760
Funding
European Comission
Programme
ERC-2017-PoC
Budget
150.000 €
Our budget
150.000 €

Team

Description

Osteosarcoma is a rare but devastating bone tumour that mainly affects children, adolescents and elderly. This type of tumour is very resistant to therapy, being thus urgent to find new effective treatments. In vitro tumour models can recapitulate many aspects of the natural tumour environment, and could be used to improve the predictive value of the effect of anticancer drug candidates. The aim of MicroBone is the development of biological relevant spherical-based 3D disease models that could be used as an enabling tool for personalized and precision drug discovery, increasing our understanding of the mechanisms behind bone cancer and testing new drug-based therapies.

Coordinator

João Mano

Coordination

Universidade de Aveiro (UA)

Groups

G5 - Biomimetic, Biological and Living Materials;

link

https://cordis.europa.eu/project/rcn/213602_en.html

Outputs

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