Ongoing Supervisions
Ana Filipa Nina e Cunha
PhD Student
Beatriz Guapo Neves
PhD Student
Bruno Daniel Pinto Morais
PhD Student
Diana Fernandes Tavares
Research Fellowship
Duarte Félix Macedo
PhD Student
Eduarda Mota da Silva
Junior Researcher
Francisca Gonçalves Perfeito
PhD Student
Marlene Correia
PhD Student
Raquel Maria da Costa Gonçalves
PhD Student
Rita Neves
Research Fellowship
Rosana Martins
PhD StudentProjects
Exploring devitalized MSCs fibres as immunomodulatory devices for wound regeneration through (i) direct promotion of healing or (ii) enabling of allograft transplantation free of systemic immunosuppression (LAZARUS)
CoordinatorOther International
The project aims at exploring MSCs as constituents of off-the-shelf easy-to-handle immunomodulatory biomaterials. The project focuses on using these materials to treat difficult-to-heal wounds, which may be chronic, or have proneness to become chronic if not properly treated.Two treatment approaches will be explored using devitalized MSC aggrega...Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)
PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...Innovative tools to treat and model complex cancer environments (TheraTools)
PartnerEuropean Comission
Funded by the Marie Skłodowska-Curie Actions programme, the TheraTools project will create a multidisciplinary research and training network to focus on the technological development of scientific tools to study malignant tumours localised beyond a biological barrier, as in the case of brain tumours. The TheraTools consortium will provi...Merging Sustainable and Digital Chemical Technologies for The Development of Greener-Bydesign Pharmaceuticals (SusPharma)
PartnerEuropean Comission
Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern ...Metabolite-activated 3D stem cell differentiation into bone (BetterBone)
PartnerFundação para a Ciência e a Tecnologia
Strategies involving mesenchymal stem cell (MSC) osteogenic differentiation have emerged as promising tools in regenerative medicine. These work by either promoting in situ regeneration, or through newly-fabricated tissue grafts, potentially overcoming clinical complications related to more conventional therapies. However, bioengineered ...A Metabolomics-guided Bioreactor for Improved Engineered Bone Implants (BioImplant)
PartnerFundação para a Ciência e a Tecnologia
Advancing the Regenerative and Translational Potential of Cellular Fibers (CellFi)
CoordinatorFundação para a Ciência e a Tecnologia
Mesenchymal Stem Cells Scaffold-free Cellular Fibers RegenerationCápsulas esféricas multicompartimentalizadas de alto rendimento para a transplantação de co-culturas multimodais de células estaminais derivadas do tecido adiposo e ilhotas pancreáticas. (TranSphera)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
PartnerFundação para a Ciência e a Tecnologia
Development and testing of multifunctional carriers based on micro- and nanoscale engineering for targeted, controlled, and safe delivery of agrochemicals to crops. PTDC/BAA- Curriculum Vitae – Mariana Braga de Oliveira 11 of 19 AGR/29258/2017 (Agritarget)
PartnerFundação para a Ciência e a Tecnologia
Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Publications
Controlling the diffusion of small molecules from matrices processed by all-aqueous methodologies: towards the development of green pharmaceutical products
Bárbara S. Neves, Raquel C. Gonçalves, João F. Mano, Mariana B. Oliveira
2024, Green Chemistry.
Natural polymer‐polyphenol bioadhesive coacervate with stable wet adhesion, antibacterial activity, and on‐demand detachment
Margarida MA Sacramento, Mariana B Oliveira, José RB Gomes, João Borges, Benjamin R Freedman, David J Mooney, João MM Rodrigues, João F Mano
2024, Advanced Healthcare Materials, 13.
Encapsulated Mesenchymal Stromal Cells as Cyclic Providers of Immunomodulatory Secretomes: a living on‐Demand Delivery System
Ana Rita Sousa, Diana C Gonçalves, Beatriz Guapo Neves, Ana Santos‐Coquillat, Mariana B Oliveira, João F Mano
2024, Advanced Healthcare Materials.
Shape‐Versatile Fixed Cellular Materials for Multiple Target Immunomodulation
Ana Rita Sousa, Ana Filipa Cunha, Ana Santos‐Coquillat, Beatriz Hernaez Estrada, Kara Spiller, Marta Barão, Artur Filipe Rodrigues, Susana Simões, Andreia Vilaça, Lino Ferreira, Mariana B Oliveira, João F Mano
2024, Advanced Materials.
Spontaneous Formation of Solid Shell Polymeric Multicompartments at All-Aqueous Interfaces
Francisca G. Perfeito, Sara Vilabril, Andreia Cerqueira, Mariana B. Oliveira, João F. Mano
2024, Advanced Science.
Reversible imine crosslinking in waterborne self-healing polymer coatings
Martins, TD; Viciosa, MT; Oliveira, MB; Fernandes, A; Mano, JF; Baleiza, C; Farina, JPS
2023, PROGRESS IN ORGANIC COATINGS, 180.
Advanced hydrogels based on natural macromolecules: chemical routes to achieve mechanical versatility
Mortier, C; Costa, DCS; Oliveira, MB; Haugen, HJ; Lyngstadaas, SP; Blaker, JJ; Mano, JF
2022, MATERIALS TODAY CHEMISTRY, 26.
AIR-FOAMED HYDROGELS FOR HOMOGENOUS CELL VIABILITY IN LARGE CONSTRUCTS
Salvador, T; Oliveira, MB; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S401-S401.
All-Aqueous Freeform Fabrication of Perfusable Self-Standing Soft Compartments
Goncalves, RC; Vilabril, S; Neves, CMSS; Freire, MG; Coutinho, JAP; Oliveira, MB; Mano, JF
2022, Advanced Materials, 34, 31.
An Intracellular Metabolic Signature as a Potential Donor-Independent Marker of the Osteogenic Differentiation of Adipose Tissue Mesenchymal Stem Cells
Bispo, DSC; Jesus, CSH; Romek, K; Marques, IMC; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 23.
