Ongoing Supervisions
Adriana Gomes
PhD Student
Amália Gomes
Research Fellowship
Ana Cristina Quintans da Silva
PhD Student
Anna Raffaela de Matos
Junior Researcher
Ariana Santos
PhD Student
João Maria Silva Pinto Leite
PhD Student
João Pedro Fernandes Carvalho
PhD Student
Maria do Céu Esteves Amaral Teixeira
PhD Student
Márcia Dias Braz
PhD StudentProjects
Engineering self-propelled cellulose-based Janus microrobots (Cell4Janus)
PartnerFundação para a Ciência e a Tecnologia
From Fossil To Forest (FF2F (Biocomposites))
Local CoordinatorIndustry National
This Innovation Pact is aimed at developing cellulose-based packaging and products to replace fossil-based plastics. In this context, it comprises the following six work packages: (1) high yield pulp and brown paper; (2) paper with increased mechanical strength; (3) paper with barrier properties; (4) biocomposites; (5) paper sensors for...Pacto da Bioeconomia azul (BIOECOAZUL (Termoendurecíveis))
Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...Pacto da Bioeconomia azul (BIOECOAZUL (Termoplásticos a desenvolver))
Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...Pacto da Bioeconomia azul (BIOECOAZUL (Plásticos já existentes))
Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...Bacterial Cellulose Membranes for Proton Exchange Fuel Cells (EXPL/CTM-ENE/0548/2012)
PartnerFundação para a Ciência e a Tecnologia
Bacterial cellulose fuell cells proton exchange membranes in situ polymerization/graftingBIOBLOCKS - Concepção de produtos de base biológica como percursores para a bioindústria de síntese química e de biomateriais a pertir de fontes renováveis lenhocelulósicas (BioBlocks)
Local CoordinatorIndustry National
O aumento dos preços de petróleo e uma maior apetência dos consumidores por produtos ecológicos e sustentáveis, têm vindo a viabilizar progressivamente o processo de produção e comercialização de biocombustíveis, bioquímicos e biopolímeros com base em materiais de fontes renováveis alternativos aos de origem petroquímica, permitindo a emergência...Bioeconomia para Têxtil e Vestuário (BE@T)
Local CoordinatorIndustry National
Apoiada pelo Plano de Recuperação e Resiliência (PRR), a indústria têxtil nacional vai investir 138 milhões de euros na bioeconomia sustentável, procurando a mudança de paradigma para o setor e a criação de produtos de alto valor ...Bioinspired nanostructured biocomposites based on proteins and polysaccharides nanofibrils (EXPL/CTM-POL/1802/2013)
CoordinatorFundação para a Ciência e a Tecnologia
Proteins and polysaccharides nanofibrils Nanostructured materials Self-assembly Biomedical applicationsControlled chemical modification of polysaccharides for the development of novel materials (PTDC/QUI/68472/2006 )
CoordinatorFundação para a Ciência e a Tecnologia
Polysaccharides Chemical modification Composites Functional materialsCorrole based systems for luminescent thermometry at nanoscale (CORLUTNA)
PartnerFundação para a Ciência e a Tecnologia
Temperature (T) is a fundamental parameter that affects the behavior of physical, chemical and biological systems in a wide variety of ways. Measuring T is important in many fields: photonic devices, nano/microelectronics, medical diagnostics, nanomedicine. Regarding the several classes of thermometers, one possible approach is to use dye lumine...DeepBiorefinery - Natural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefinerie (DeepBiorefinery )
PartnerFundação para a Ciência e a Tecnologia
natural deep eutetic solvents, biorefinery, green separation processesDesenvolvimento de rolhas de cortiça produzidas por processos mais verdes e sustentáveis (GCORK)
PartnerIndustry National
"O Projeto GCORK tem por objetivo capacitar a Amorim Cork a ser a primeira empresa a lançar no mercado uma gama de rolhas de cortiça aglomerada com colas e tratamentos de superfície Bio, produzidas por processos mais verdes e mais sustentáveis. Este produto será extremamente inovador po...Development of new polyesters derived from 2,5-furandicarboxylic acid (PTDC/QUI-QUI/101058/2008)
PartnerFundação para a Ciência e a Tecnologia
2,5-furandicarboxylic acid Polyesters synthesis Materials from renewable sources BiorefineryEngenharia de nanofibras de origem biológica para o desenvolvimento de biotintas nanoestruturadas de elevada performance para bio-impressão 3-D (NANOBIOINKS)
PartnerFundação para a Ciência e a Tecnologia
Eucalyptus triterpenic biological activity (PTDC/AGR-FOR/3187/2012)
Local CoordinatorFundação para a Ciência e a Tecnologia
Eucalyptus spp Ionic Liquids Antitumoral Activity MetabolomicsFLUI - Sistemas de extrusão duplo paralelo de ácido polilático com injeção modular de compostos bioativos para a produção de filmes flexíveis mono e multi-camada biofuncionais para embalagens de produtos alimentares a partir de resíduos lenho-celulós (FLUI)
PartnerIndustry National
A solução apresentada pelo projeto FLUI visa o sucesso da obtenção de equipamentos inovadores e disruptivos com as soluções presentes no mercado (TRL6) para a produção de filmes flexíveis biofuncionais com flexibilidade, mono e multicamada...Green chemicals and technologies for the wood-to-textile value chain. (GRETE)
PartnerEuropean Comission
The GRETE project will tackle the challenges caused by increased global demand for sustainable textile fibres by offering new breakthroughs in the wood-to-textile value chain. The substitution of cotton by man-made cellulose fibres is also necessary because of sustainability issues. Currently the raw material base for the production of man-made ...GREENPEC - Desenvolvimento de um plastificante primário para PVC, de origem animal e livre de ftalatos (GREENPEC )
PartnerIndustry National
O objetivo principal deste projeto, levado a cabo pelo consórcio entre a Sapec Química e a Universidade de Aveiro, consiste no desenvolvimento de um plastificante primário para PVC originado a partir de óleos vegetais, os quais são considerados recursos renováveis e agentes de crescimento sustentável. Com o cumprimento destes objetivos, prevê-se...INNOVATE-Implantable Organic Devices for Advanced Therapies (INNOVATE)
Local CoordinatorFundação para a Ciência e a Tecnologia
Bioelectronica; Transdutores electrónicos implantáveis; Medicina regenerativa; Sinais bioelectrónicosInnovative Products and Technologies from Eucalyptus Project (InPacTus)
PartnerIndustry National
Inpactus, to be developed by the Consortium, aims to develop new solutions, such as cellulosic pulps with innovative features, new paper products with different specificities and functions, tissue paper with innovative properties, new bioproducts, biofuels and other materials obtained from the deconstruction and conversion of forest biomass and ...Inovação na Fileira da Resina Natural para Reforço da Bioeconomia Nacional (RN21)
PartnerIndustry National
A transição para uma economia mais sustentável, oferece inúmeras oportunidades para revitalizar os setores mais tradicionais da economia portuguesa, onde destacamos a produção e transformação da resina natural.O Projeto Integrado RN21 – Ino...Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials (PTDC/SAU-TOX/120953/2010)
PartnerFundação para a Ciência e a Tecnologia
metabolic profiling and metabonomics silver nanoparticles toxicological and biological effects nanotoxicologyPublications
Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive Compounds
Sousa, JLC; Freire, CSR; Silvestre, AJD; Silva, AMS
2019, MOLECULES, 24, 2.
The Health-Promoting Potential of Salix spp. Bark Polar Extracts: Key Insights on Phenolic Composition and In Vitro Bioactivity and Biocompatibility
Ramos, PAB; Moreirinha, C; Silva, S; Costa, EM; Veiga, M; Coscueta, E; Santos, SAO; Almeida, A; Pintado, MM; Freire, CSR; Silva, AMS; Silvestre, AJD
2019, ANTIOXIDANTS, 8, 12.
ISBN:
2076-3921
Hydrotropy and Cosolvency in Lignin Solubilization with Deep Eutectic Solvents
Soares, B; Silvestre, AJD; Pinto, PCR; Freire, CSR; Coutinho, JAP
2019, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 7, 14, 12485-12493.
Deep eutectic solvents comprising active pharmaceutical ingredients in the development of drug delivery systems
Pedro, SN; Freire, MG; Freire, CSR; Silvestre, AJD
2019, EXPERT OPINION ON DRUG DELIVERY, 16, 5, 497-506.
ISBN:
1744-7593
Design of Nonsteroidal Anti-Inflammatory Drug-Based Ionic Liquids with Improved Water Solubility and Drug Delivery
Chantereau, G; Sharma, M; Abednejad, A; Neves, BM; Sebe, G; Coma, V; Freire, MG; Freire, CSR; Silvestre, AJD
2019, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 7, 16, 14126-14134.
Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded with phenolic-based ionic liquids for cutaneous application
Morais, ES; Silva, NHCS; Sintra, TE; Santos, SAO; Neves, BM; Almeida, IF; Costa, PC; Correia-Sa, I; Ventura, SPM; Silvestre, AJD; Freire, MG; Freire, CSR
2019, CARBOHYDRATE POLYMERS, 206, 187-197.
ISBN:
1879-1344
Physicochemical surface properties of bacterial cellulose/polymethacrylate nanocomposites: an approach by inverse gas chromatography
Faria, M; Vilela, C; Silvestre, AJD; Deepa, B; Resnik, M; Freire, CSR; Cordeiro, N
2019, CARBOHYDRATE POLYMERS, 206, 86-93.
ISBN:
1879-1344
Poly(glycidyl methacrylate)/bacterial cellulose nanocomposites: Preparation, characterization and post-modification
Faria, M; Vilela, C; Mohammadkazemi, F; Silvestre, AJD; Freire, CSR; Cordeiro, N
2019, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 127, 618-627.
ISBN:
1879-0003
Nanocellulose-based antifungal nanocomposites against the polymorphic fungus Candida albicans
Vilela, C; Oliveira, H; Almeida, A; Silvestre, AJD; Freire, CSR
2019, CARBOHYDRATE POLYMERS, 217, 207-216.
ISBN:
1879-1344
Zwitterionic Nanocellulose-Based Membranes for Organic Dye Removal
Vilela, C; Moreirinha, C; Almeida, A; Silvestre, AJD; Freire, CSR
2019, MATERIALS, 12, 9.
Advanced Nanocellulose-Based Materials: Production, Properties and Applications
C. Vilela; C.S.R. Freire
2022, MDPI.
ISBN:
978-3-0365-3190-8
Advanced Biopolymer-Based Nanocomposites and Hybrid Materials
Armando J. D. Silvestre; Carmen S.R. Freire; Carla Vilela
2021, Basel, MDPI.
ISBN:
978-3-0365-0511-4
Polysaccharide Based Hybrid Materials, Metals and Metal Oxides, Graphene and Carbon Nanotubes
Carla Vilela, Ricardo J. B. Pinto, Susana Pinto, Paula Marques, Armando J. D. Silvestre, Carmen S. R. Freire
2018, Springer.
ISBN:
978-3-030-00347-0
Active packaging
In Galanakis, Charis (Eds.), Sustainable Food Processing and Engineering Challenges
Carvalho, João P.F.; Freire, Carmen S.R.; Vilela, Carla
2021, Academic Press.
ISBN:
9780128227145
Modification of textiles for functional applications
In Md. Ibrahim H. Mondal (Eds.), Fundamentals of Natural Fibres and Textiles
Ana C. Q. Silva, Armando J. D. Silvestre, Carmen S. R. Freire, Carla Vilela
2021, 303-365, Elsevier.
ISBN:
9780128214831
Furanoate-Based Nanocomposites: A Case Study Using Poly(Butylene 2,5-Furanoate) and Poly(Butylene 2,5-Furanoate)-co-(Butylene Diglycolate) and Bacterial Cellulose
In George Z. Papageorgiou (Eds.), Polymers from Renewable Resources
Marina Matos, Andreia Sousa, Nuno H.C.S. silva, Carmen S.R. Freire, Márcia Andrade, Adélio Mnedes, Armando J.D. Silvestre
2018, MDPI.
ISBN:
978-3-03897-451-2
Development and applications of cellulose nanofibres based polymer nanocomposites
In Ehsan Bafekrpour (Eds.), Advanced Composite Materials: Properties and Applications
Carla Vilela, Ricardo J. B. Pinto, Ana R. P. Figueiredo, Carlos Pascoal Neto, Armando J. D. Silvestre, Carmen S. R. Freire
2017, 1-65, Warsaw/Berlin, De Gruyter Open.
ISBN:
9783110574432
Antimicrobial Properties and Therapeutic Applications of Silver Nanoparticles and Nanocomposites
In Alexandru Mihai Grumezesc (Eds.), Antimicrobial Nanoarchitectonics - From Synthesis to Applications
R.J.B. Pinto, M. Nasirpour, J. Carrola, H. Oliveira, C.S.R. Freire, I.F. Duarte
2017, 223-259, Elsevier.
ISBN:
978-0-323-52733-0
Polyethylene Terephthalate: Copolyesters, Composites, and Renewable Alternatives
In P. M. Visakh Mong Liang (Eds.), Poly(ethylene Terephthalate) Based Blends, Composites and Nanocomposites.
Andreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho
2015, 111-139, Elsevier Science Ltd.
ISBN:
9780323313063
Recent advances on the development of antibacterial polysaccharide-based materials, Chitosan, cellulose and starch
In Ramawat, Kishan Gopal, Mérillon, Jean-Michel (Eds.), Polysaccharides: Bioactivity and Biotechnology
V. Coma, C.S.R. Freire and A.J.D. Silvestre
2015, 1751-1803, New York, Springer International Publishing.
ISBN:
978-3-319-16297-3
Polyethylene Terephthalate: Copolyesters, Composites, and Renewable Alternatives
In Visakh P.M., Mong Liang (Eds.), POLY(ETHYLENE TEREPHTHALATE) BASED BLENDS, COMPOSITES AND NANOCOMPOSITES
Andreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho
2015, Elsevier Inc..
ISBN:
978-0-323-31306-3
2 Bacterial Cellulose-Based Nanocomposites: Roadmap for Innovative Materials
Nanocellulose Polymer Nanocomposites: Fundamentals and Applications
A. R. P. Figueiredo, C. Vilela, C. Pascoal Neto, A.J.D. Silvestre and C.S.R. Freire
2014, Scrivener, Willey.
ISBN:
978-1-118-87190-4
The bulk oxypropylation of chitin and chitosan and the characterization of the ensuing polyols
In Senel S, Vårum KM Sumnu MM Hincal AA (Eds.), Advances In Chitin Science
Fernandes S, Freire CSR, Pascoal Neto C, Gandini A
2007, 10, 530-535, Antalya.
ISBN:
978-975-491-250-0
Advanced Nanocellulose-Based Materials: Production, Properties and Applications
C. Vilela; C.S.R. Freire
2022, MDPI.
ISBN:
978-3-0365-3190-8
Advanced Biopolymer-Based Nanocomposites and Hybrid Materials
Armando J. D. Silvestre; Carmen S.R. Freire; Carla Vilela
2021, Basel, MDPI.
ISBN:
978-3-0365-0511-4
Polysaccharide Based Hybrid Materials, Metals and Metal Oxides, Graphene and Carbon Nanotubes
Carla Vilela, Ricardo J. B. Pinto, Susana Pinto, Paula Marques, Armando J. D. Silvestre, Carmen S. R. Freire
2018, Springer.
ISBN:
978-3-030-00347-0
Biofuncionalização de nanocristais de celulose para o desenvolvimento de novos sistemas para tratamento e diagnóstico do cancro
Diogo Pinheiro
2018, supervised by Carmen Freire and Ricardo Pinto.
Biofuncionalização de nanocristais de celulose com ácido fólico para o desenvolvimento de novos sistemas para o diagnóstico e tratamento do cancro
Nicole Silva Lameirinhas
2017, supervised by Ricardo Pinto and Carmen Freire.
Biofuncionalização de nanocristais de celulose com ácido fólico para o desenvolvimento de novos sistemas para o diagnóstico e tratamento do cancro
Fátima Gabriela Guedes Faria
2017, supervised by Carmen Freire and Ricardo Pinto.
Biosynthesis of metallic nanostructures using natural extracts: study of structural and morphological features and evaluation of its therapeutic potential
Madalena Pinheiro Morais
2016, supervised by Ricardo Pinto and Carmen Freire .
Biosynthesis of metallic nanostructures using natural extracts: study of structural and morphological features and evaluation of its therapeutic potential
Catarina dos Reis Viegas
2015, supervised by Carmen Freire and Ricardo Pinto.
Green reduction of graphene oxide with Eucalyptus globulus bark extract
Mariana Rodrigues Ferreira da Silva
2015, supervised by Carmen Freire and Ricardo Pinto.
Characterization of new nanocomposites based on natural matrices (cellulose) and metallic nanostructures of copper
Kornelia Pielak
2014, supervised by Carmen Freire and Ricardo Pinto.
Desenvolvimento de novos nanomateriais híbridos a partir de biopolímeros e nanopartículas metálicas para aplicação em biosensores e catálise
Joana Filipa Martinho Lopes
2014, supervised by Carmen Freire and Ricardo Pinto.
Copper, cobalt, nickel, and zinc metallodrugs with antibacterial activity
Gomes, Adriana; Pereira, Carla; Mendes, Ricardo; Paz, Filipe; Almeida, Adelaide; Santos, T. M.; Freire, Carmen; Leite Ferreira, B. J. M
2022.
Metallodrugs with antibacterial activity and their incorporation into nanocellulose membranes for wound healing applications
Gomes, Adriana; Pereira, Carla; Mendes, Ricardo; Paz, Filipe; Almeida, Adelaide; Santos, T. M.; Freire, Carmen; Leite Ferreira, B. J. M.
2022.
Biosorbent films based on nanocellulose and lysozyme nanofibers for efficient removal of mercury (II) from natural waters
Silva, N; Figueira, P; Vilela, C; Pinto, R; Marrucho, I; Periera, M; Freire, C
2018, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 255.
Novel multilayered nanostructured drug delivery systems obtained by layer-by-layer assembly of cellulose nanocrystals
Maia. M, Vilela. C, Pinto. R, Valente. B, Carvalho. T, Freire. C
2018.
Patents
Aqueous coating compositions for use in surface treatment of cellulosic substrates
Products InternationalNational
Neto, Carlos; Barros, Carmen; Fernandes, Susana; Silvestre, Armando; Gandini, Alessandro;
The present invention relates with the application of novel coating compositions, containing chitosan (and its derivatives) and bacterial cellulose, for the improvement of the final properties of cellulosic based materials, like paper and textile materials. The process involves the preparation of homogeneous bacterial cellulose-chitosan...Method for Obtaining na Extract Rich in Triterpenic Acids From Eucalyptus Barks
Processes InternationalNational
Domingues, Rui ; Barros, Carmen; Silvestre, Armando; Neto, Carlos; Silva, Carlos;
The present invention relates to a method of obtaining extracts having very high contents (up to 98%) of triterpenic acids, mainly oleanolic and ursolic acids, from Eucalyptus barks. The method involves the solid-liquid extraction of the bark with organic solvents, preferably hexane, and the fractionation of the crude extract by means o...