Carmen Sofia da Rocha Freire Barros

Coordinating Researcher

Short CV

 

Researcher ID :  http://www.researcherid.com/rid/E-4549-2013

 

Carmen Freire was born in 1976 in Venezuela. In 1994 she concluded high school at Escola Secundária José Estevão (Aveiro), and, motivated by an enormous interest in Chemistry, started her graduation in Industrial Chemistry at the University of Aveiro (UA).

 

After concluding her graduation in 1998, she started her PhD work, “Eucalyptus globulus Low Molecular Weight Organic Compounds: Behavior During Wood Kraft Pulping and Pulp Bleaching”, at the Chemistry Department of the University of Aveiro. In early 2003, she embraced a post-doctoral project on “Surface Chemical Modification of Cellulose Fibers for Novel Paper and Composite Materials”, developed jointly between the Department of Chemistry of UA and the EFPG (presently Pagora), Institut Polytechnique de Grenoble a forefront research group in the domain of Macromolecular Materials from Renewable Resources. During this period, she got a solid background and knowledge on the development and characterization of natural polymers-based materials.

 

Since 2006, as a Auxiliary Reseracher (from January 2006 to June 2011) and now as a Principal Researcher (FCT Researcher), she has leaded the research on materials and composites from cellulose and other polysaccharides within BioPol4Fun group at CICECO/UA .

 

Main achievements:

 

  • 164 articles in SCI journals (December 2018).
  • 3 National patents and 2 European patent.
  • More than 170 communications in International Conferences
  • Referee for several high impact factor international journals in the areas of biomacromolecules, polysaccharides, green and sustainable chemistry and materials in general
  • Concluded the supervision of 3 PhD, 3 Post-Docs, 31 Master theses,

Scientific Interests

Her research interests are centred on the Chemistry of polymers from renewable resources (caracterization and application) and development of new sustainable composite materials and  nanostructured materails  for disntinct appications

 

Present Research Group

BioPol4Fun- Innovation in biopolymeric functional materials and bioactive compounds

Supervisor or co-supervisor of 5 Pos-doctorate students, 10 PhD student and 4 Master students.

Main present collaborators

 

Armando Silvestre, Ana Barros-Timmons, Mara Freire, João Coutinho,Graça Neves, Paulo Claro, Iola Duarte  e Filipe Figueiredo (Department of Chemistry, University of Aveiro),

Adelaide Almeida, Helena Oliveira (Department of Biology, University of Aveiro)

Paula Alexandrina Marques (TEMA, University of Aveiro)

Isabel Marrucho (IST)

Fátima Duarte (CEBAL, Beja)

Catarina Rosado (Universidade Lusófona, Lisboa)

Isabel Almeida e Paulo Costa (Faculty of Pharmacy, University of Porto)

Fernando Dourado e Miguel Gama (University of Minho)

 

Stefan Spirk (TU Graz,  Austria)

Hélder Santos (University of Helsinki, Finland)

Pedro Fardim  (Abo Akademi, Finland and University of Leuven, Belgium)

Ana Alonsa Varona (UPV, San Sebastian)

Patrizia Sadocco (SSCCP, Stazione Sperimentale Carta, Cartoni e Paste per Carta, Italy)

 

 

Selected Publications

 

Nuno H.C.S. Silva, Carla Vilela, Adelaide Almeida, Isabel M. Marrucho, Carmen S.R.Freire, Pullulan-based nanocomposite films for functional food packaging: Exploiting lysozyme nanofibers as antibacterial and antioxidant reinforcing additives, Food Hydrocolloids, 2018, 77, 921-930.

Louise Saidi, Carla Vilela, Helena Oliveira, Armando J.D. Silvestre, Carmen S.R. Freire, “Poly(N-methacryloyl glycine)/nanocellulose composites: pH-sensitive systems for controlled release of diclofenac”, Carbohydr. Polym., 2017, 169, 357-365.

Carla Vilela, Ricardo J. B. Pinto, Joel Coelho, M. R. M. Domingues, Sara Daina, Patrizia Sadocco, Sónia A. O. Santos, Carmen S. R. Freire, Bioactive chitosan/ellagic acid films with UV-light protection for active food packaging, Food Hydrocolloids, 2017, 73, 120-128.        

Joana F.B. Barata, Ricardo J.B. Pinto, Vanda I.R.C. Vaz Serra, Armando J.D. Silvestre, Tito Trindade, Maria Graça P.M.S. Neves, José A.S. Cavaleiro, Sara Daina, Patrizia Sadocco, Carmen S.R. Freire, “Fluorescent bioactive corrole grafted-chitosan films”, Biomacromolecules, 2016, 17, 1395-1403.                                                                                                                      

Liliana C. Tomé, Ricardo J. B. Pinto, Eliane Trovatti, Carmen S. R. Freire, Armando J. D. Silvestre, Carlos Pascoal Neto, Alessandro Gandini, Transparent bionanocomposites with improved properties prepared from acetylated bacterial cellulose and poly(lactic acid) through a simple approach, Green Chem., 2011, 13, 419-427

Present projects

NanoBioinks- Engineering bio-based nanofibers for the development of high performance bioinks for 3D bioprinting”, CENTRO-01-0145-FEDER-031289, FCT/MCTES, (PI), 2018-                                                                                                                 
CORLUTNA- Systems based on corrolic macrocycles for luminescent thermometry  at nanoscale”, Projeto nº 031523 com o apoio financeiro da Fundação para a Ciência e Tecnologia/MCTES,  (co-PI) 2018-                                                                                             
“InPaCTus-  Products and Technologies from eucalipt”, RCI, I&DANI/AICEP, coordinated by Navigator Company, (PI of 3 sub-projects)

                                          
MultiBiorefinery – Estratégias multiuso para a valorização de uma gama alargada de subprodutos agroflorestais e das pescas: Um passo em frente na criação de uma biorrefinaria integrada” (POCI-01-0145-FEDER-016403), (team member)                                       
“AgroForWealth – Biorefinery of agro-forest residues: a strategy for the valorization of resources for wealth and sustainability“; CCDRC (team member) 

                            
INNOVATE- Implantable organic Devices for advanced therapies”, University of Algarve, University of Aveiro, PTDC/EEI-AUT/5442/2014, (PI at UA)


DeepBiorefinery: "Natural Deep eutectic solvents: a platform to boost Eucalyptus globulus and Quercus suber cork integrated biorrefinery”, Universidade de Aveiro e ITQB. PTDC/AGR-TEC/1191/2014 (team member)

Ongoing Supervisions

Projects

Cell4Janus - Engineering self-propelled cellulose-based Janus microrobots (Cell4Janus)

PartnerFundação para a Ciência e a Tecnologia
The goal of the Cell4Janus project is to develop, characterize, and assess the performance of a new generation of cellulose-based materials endowed with mobility. The novelty of this proposal lies in the microfluidics-assisted fabrication of multifunctional cellulose-derived microparticles through dissolution in green-oriented neoteric ...

From Fossil To Forest (FF2F (Biocomposites))

Local CoordinatorIndustry National
This Innovation Pact is aimed at developing cellulose-based packaging and products to replace fossil-based plastics. In this context, it comprises the following six work packages: (1) high yield pulp and brown paper; (2) paper with increased mechanical strength; (3) paper with barrier properties; (4) biocomposites; (5) paper sensors for...

Inovação na Fileira da Resina Natural para Reforço da Bioeconomia Nacional (RN21)

PartnerIndustry National
A transição para uma economia mais sustentável, oferece inúmeras oportunidades para revitalizar os setores mais tradicionais da economia portuguesa, onde destacamos a produção e transformação da resina natural.O Projeto Integrado RN21 – Inovação na Fileira da Resina Natural para Reforço da Bioeconomia Nacional, assenta em três grandes princípios...

Pacto da Bioeconomia azul (BIOECOAZUL (Termoendurecíveis))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Pacto da Bioeconomia azul (BIOECOAZUL (Termoplásticos a desenvolver))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Pacto da Bioeconomia azul (BIOECOAZUL (Plásticos já existentes))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Publications

Combined effect of SAR- endolysin LysKpV475 with polymyxin B and Salmonella bacteriophage phSE-5

Gontijo, M; Teles, MP; Correia, HM; Jorge, GP; Goes, ICRS; Flores, AJF; Braz, M; Ceseti, LD; Ramos, PZ; Silva, IRE; Vidigal, PMP; Kobarg, J; Couñago, RM; Alvarez-Martinez, CE; Pereira, C; Freire, CSR; Almeida, A; Brocchi, M
2024, MICROBIOLOGY-SGM, 170, 5.
ISBN: 1465-2080

Wood inspired biobased nanocomposite films composed of xylans, lignosulfonates and cellulose nanofibers for active food packaging

Silva, JM; Vilela, C; Girao, AV; Branco, PC; Martins, J; Freire, MG; Silvestre, AJD; Freire, CSR
2024, CARBOHYDRATE POLYMERS, 337.
ISBN: 1879-1344

Flexible monolayer films of poly(lactic acid)/gallic acid for active food packaging: Preparation, characterization, and bioactive properties

Karamysheva, A; Silva, JM; Facchinatto, WM; Braz, MD; Almeida, A; Silvestre, AJD; Freire, CSR; Vilela, C
2024, JOURNAL OF APPLIED POLYMER SCIENCE, 141, 32.
ISBN: 1097-4628

Implantable Patch of Oxidized Nanofibrillated Cellulose and Lysozyme Amyloid Nanofibrils for the Regeneration of Infarcted Myocardium Tissue and Local Delivery of RNA-Loaded Nanoparticles

Carvalho, T; Bártolo, R; Correia, A; Vilela, C; Wang, SQ; Santos, HA; Freire, CSR
2024, MACROMOLECULAR RAPID COMMUNICATIONS, 45, 15.
ISBN: 1521-3927

Trilayered nanocellulose-based patches loaded with acyclovir and hyaluronic acid for the treatment of herpetic lesions

Silva, ACQ; Mendes, M; Vitorino, C; Montejo, U; Alonso-Varona, A; Silvestre, AJD; Vilela, C; Freire, CSR
2024, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 277.
ISBN: 1879-0003

Potential of bacteriophage phT4A as a biocontrol agent against Escherichia coli in food matrices

Braz, M; Pereira, C; Freire, CSR; Almeida, A
2024, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 424.
ISBN: 1879-3460

Biobased hydrogel bioinks of pectin, nanocellulose and lysozyme nanofibrils for the bioprinting of A375 melanoma cell-laden 3D in vitro platforms

Teixeira, MC; Lameirinhas, NS; Carvalho, JPF; Luís, J; Oliveira, H; Oliveira, JM; Silvestre, AJD; Vilela, C; Freire, CSR
2024, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 282.
ISBN: 1879-0003

Switchable adhesive films of pullulan loaded with a deep eutectic solvent-curcumin formulation for the photodynamic treatment of drug-resistant skin infections

Pedro, SN; Valente, BFA; Vilela, C; Oliveira, H; Almeida, A; Freire, MG; Silvestre, AJD; Freire, CSR
2023, MATERIALS TODAY BIO, 22.

Functional fibers from regenerated wood pulp cellulose and a natural-based phytate with enhanced flame retardancy properties

Matos, FS; Fateixa, S; von Weymarn, N; Freire, CSR; Silvestre, AJD; Vilela, C
2023, JOURNAL OF APPLIED POLYMER SCIENCE, 140, 34.

Solventless Photopolymerizable Paper Coating Formulation for Packaging Applications

Silva, FM; Pinto, RJB; Barros-Timmons, A; Freire, CSR
2023, POLYMERS, 15, 5.

Patents

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